As many as 480 newborns died in the ICU of Civil Hospital Mithi during the first eight months of 2026, according to hospital sources.
Sources said 2,273 newborns were admitted to the ICU from January to August, out of which 480 died during treatment.
A total of 1,387 newborns were discharged after recovery, while 106 were shifted to other hospitals, according to the available figures.
Another 126 children were taken away by their parents against medical advice.
Hospital sources said the highest number of newborn admissions was recorded in May, when 365 babies were brought to the ICU.
Malnutrition, low birth weight and different illnesses have been identified as the main causes behind the deaths.
Sources said malnutrition and early-age marriages are also contributing to low birth weight and poor nutrition among children in Tharparkar.
The latest figures have emerged amid wider concerns about child health in Sindh.
In a separate case in Karachi, more than 100 children tested positive for HIV after receiving treatment at the government-run Kulsum Bai Valika Social Security SITE Hospital.
Health authorities said 107 children from Orangi Town tested positive for HIV, while nine infected children from Zia Colony died.
Several affected families alleged that contaminated syringes were reused on children at the hospital, causing the spread of the virus.
Federal Health Minister Syed Mustafa Kamal had earlier also said the outbreak was linked to the reuse of contaminated syringes at Valika Hospital.
Attempts were made to contact the administration of Civil Hospital Mithi for further comments on the newborn deaths and related health concerns, but no additional details were provided.
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